In this episode, Drs. Ahmad Masri and Kevin Alexander review emerging clinical data in transthyretin amyloid cardiomyopathy (ATTR-CM) presented at the Heart Failure Society of America Annual Scientific Meeting and the American Heart Association Scientific Sessions 2025, including key findings from the ATTRibute-CM and HELIOS-B trials. The discussion highlights recent publications evaluating currently available disease-modifying therapies. Drs. Masri and Alexander translate these new data into practical insights for clinicians, focusing on how evolving evidence may influence treatment selection, therapeutic sequencing, and integration of disease-modifying therapies into everyday clinical practice.

In this episode, Gregory Piazza, MD, FACC, Elvira Grandone, MD, PhD, and Abbey R. Kruper, PsyD, ABPP walk through the clinical and emotional challenges of the link between thrombosis and fertility. They discuss how clotting disorders can influence infertility, what this means for future thrombotic and cardiovascular risk, and how to support patients who are already managing significant stress. The faculty also outlines practical guidance for counseling patients who have experienced thrombosis during pregnancy or assisted reproductive therapy and who want to continue growing their families.

In this episode, Drs. Christie Ballantyne and Anne Goldberg discuss updates on familial hypercholesterolemia (FH) diagnosis and management. Recent publications in January 2026 in the Journal of Clinical Lipidology and The Journal of Pediatrics address refined diagnostic criteria and special populations including children and pregnant women. In this podcast episode, Drs. Ballantyne and Goldberg discuss the importance of early detection, genetic testing, and treatment.

To visit the course page for the Familial Hypercholesterolemia: Improving Detection to Accelerate Treatment, click here!

In this podcast, Drs. Michelle Kittleson and Jan Griffin provide a practical overview of evaluation and management of transthyretin amyloid cardiomyopathy (ATTR-CM) based on ACC's 2025 Concise Clinical Guidance document the Transthyretin Cardiac Amyloidosis Evaluation and Management: 2025 ACC Concise Clinical Guidance. The experts elaborate on key takeaways, including identifying cardiac and extra-cardiac features that raise suspicion, outlining the diagnostic pathway and screening strategies, and utilizing current disease-modifying therapies and heart failure management. Guidance on monitoring, determining treatment candidacy, and emerging future therapies is also discussed.

This podcast is supported by an educational grant from BridgeBio.

ACC Chief Innovation Officer Dr. Ami Bhatt brings together Drs. Alexandre Almorad and Christopher Porterfield to discuss how advancements in pulsed field ablation (PFA) are transforming atrial fibrillation treatment. In this episode, the participants break down the latest research in PFA and explain what that means for the procedure's safety and effectiveness.

This podcast is supported by Johnson & Johnson.

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In this episode, Prateeti Khazanie, MD, MPH, discusses common approaches to managing heart failure (HF) patients with chronic kidney disease (CKD), as well as why increased creatinine (Cr) levels should not delay HF treatment.

This podcast is part of the larger Managing HF Across the Spectrum: From Recognizing Symptoms to Implementing Appropriate Treatment grant initiative, supported by Bayer AG. To visit the Managing HF Across the Spectrum page and access additional educational activities on this topic, click here.

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"Heart Vision" is a CardiaCast podcast series stemming from the ACC Cardiovascular Imaging Section Leadership Council. This series explores emerging multimodality imaging data, evolving practice trends, disease insights, and advocacy efforts shaping the field of cardiovascular imaging.

In this episode, Dr. Purvi Parwani talks with Drs. Ron Blankstein and Lauren Baldassarre about the new 2025 ACC/AHA/ASE/ASNC/SCCT/SCMR Advanced Training Statement on Advanced Cardiovascular Imaging. They discuss why the document was needed, how it emphasizes competency-based learning, the evolving role of multimodality advanced imaging, and practical takeaways for trainees, educators, and clinicians shaping the future of the field.

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In this episode, Alison Bailey, MD, FACC, and Melvin R. Echols, MD, FACC, discuss current pharmacological and nonpharmacological interventions to prevent and/or decrease the progression of heart failure (HF).

This podcast is part of the larger Managing HF Across the Spectrum: From Recognizing Symptoms to Implementing Appropriate Treatment grant initiative, supported by Bayer AG. To visit the Managing HF Across the Spectrum page and access additional educational activities on this topic, click here.

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