Can you take too much vitamin K2? In this video, I answer the most common follow-up questions about vitamin K2, including dose, safety, testing, interactions, and whether more is actually better.

Here's the original video on the K2 clinical trial: https://youtu.be/ArxAXtzsue4

We’ll cover:
* Whether vitamin K2 toxicity is possible
* Whether using MK7 to slow coronary artery calcification is desirable
* What we know — and do not know — about upper dosing limits
* Who should be especially cautious with vitamin K supplements
* Why warfarin/Coumadin changes the conversation
* Whether vitamin K2 levels can be tested
* The difference between MK-4 and MK-7
* Whether vitamin K2 can “remove” calcium from arteries
* How I think about vitamin K2 in real-world cardiovascular prevention

The bottom line: vitamin K2 looks promising, but “promising” is not the same thing as “take as much as possible and hope your arteries applaud.”

This video is for education only and is not personal medical advice. Do not start, stop, or change supplements or medications based on YouTube — especially if you take warfarin or another medication affected by vitamin K. Talk with your own clinician.

⏰ Chapters
0:00 - More of your vitamin K2 questions
0:22 - Is softer plaque more dangerous than calcified plaque?
2:35 - Should people with high CAC avoid vitamin D3?
4:13 - Didn’t the AVADEC trial already show K2 works?
6:25 - Would a higher dose of K2 work better?
7:33 - Does K2 actively stop calcium from entering plaque?
8:28 - Can too much vitamin K2 cause blood clots?
8:55 - Vitamin K2 and warfarin/Coumadin
9:48 - Is K2 safe with Eliquis or Xarelto?
10:23 - Is 100 mcg enough—or should you take more?
11:16 - Can vitamin K2 remove calcium from arteries?
11:53 - Can you test for vitamin K deficiency?
12:37 - MK-4 vs MK-7: which form is better?
13:25 - Food sources vs K2 supplements
14:33 - Should K2 be taken with vitamin D3?
14:58 - Final takeaways

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🧬 About Dr. Lily Johnston

Dr. Johnston is a double board-certified vascular and general surgeon in San Diego, specializing in metabolic and cardiovascular prevention. She’s the founder of CorSight Health and a passionate advocate for reimagining how medicine approaches chronic disease.

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