Credits: 0.25 AMA PRA Category 1 Credit™ CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-488

Overview: Stimulants have long been used to treat attention-deficit/hyperactivity disorder (ADHD); however, their mechanisms of action have been unclear. In this episode, we review a study on functional MRI to assess brain function in patients with ADHD, providing insight into the effects of stimulant medications.

Episode resource links:

• https://doi.org/10.1016/j.cell.2025.11.039

Guest: Robert A. Baldor MD, FAAFP Music Credit: Matthew Bugos

Thoughts? Suggestions? Email us at FranklySpeaking@pri-med.com

The views expressed in this podcast are those of Dr. Domino and his guests and do not necessarily reflect the views of Pri-Med.

Credits: 0.25 AMA PRA Category 1 Credit™ CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-487

Overview: With online access driving a dramatic surge in gambling addiction, primary care clinicians are increasingly positioned on the front lines of identification and intervention. This episode brings you practical screening tools, evidence-based treatment strategies, and prevention approaches to confidently address gambling disorder in your patients.

Episode resource links:

• Yeola A, Allen MR, Desai N, et al. Growing Health Concern Regarding Gambling Addiction in the Age of Sportsbooks. JAMA Intern Med. 2025;185(4):382–389. doi:10.1001/jamainternmed.2024.8193

• Moreira D, Azeredo A, Dias P. Risk Factors for Gambling Disorder: A Systematic Review. J Gambl Stud. 2023;39(2):483-511. doi:10.1007/s10899-023-10195-1

• Ioannidis K, Del Giovane C, Tzagarakis C, et al. Pharmacological management of gambling disorder: A systematic review and network meta-analysis. Compr Psychiatry. 2025;137:152566. doi:10.1016/j.comppsych.2024.152566

• Ulisse, K., Albitar, J., Aromin, J. T., & Berry, J. (2025). Emerging Interventions in Behavioral Addictions: A Narrative Review of Psychedelics and Neuromodulation. Brain sciences, 15(9), 980. https://doi.org/10.3390/brainsci15090980

• Identifying a gambling disorder: Mass.gov Practice Guidelines for Treating Gambling-Related Problems. Includes brief screening, Assessment, Diagnosis, Hotlines and Resources.

• Gambling Addiction Calendar: Free app

• Reset App: Free

Guest: Jill M. Terrien PhD, ANP-BC Music Credit: Matthew Bugos

Thoughts? Suggestions? Email us at FranklySpeaking@pri-med.com

The views expressed in this podcast are those of Dr. Domino and his guests and do not necessarily reflect the views of Pri-Med.

Credits: 0.25 AMA PRA Category 1 Credit™ CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-486

Overview: Optimizing diabetes management starts with choosing the right medication for the patient. Listen in as we discuss current prescribing recommendations, empowering you to confidently compare medication classes and select therapies that best fit individual patient needs—while prioritizing kidney protection to reduce the risk of long-term complications.

Episode resource links:

• Jensen SK, Heide-Jørgensen U, Andersen IT, et al. SGLT2 Inhibitors vs GLP-1 Receptor Agonists for Kidney Outcomes in Individuals With Type 2 Diabetes. JAMA Intern Med. Published online January 20, 2026. doi:10.1001/jamainternmed.2025.7409
• Samson SL, et al. American Association of Clinical Endocrinology consensus statement: comprehensive type 2 diabetes management algorithm—2023 update. Endocr Pract. 2023;29(5):305-340.

Guest: Jillian Joseph, MPAS, PA-C Music Credit: Matthew Bugos

Thoughts? Suggestions? Email us at FranklySpeaking@pri-med.com

The views expressed in this podcast are those of Dr. Domino and his guests and do not necessarily reflect the views of Pri-Med.