In this plain language podcast, highlights from the 67th American Society of Hematology Annual Meeting and Exposition (ASH 2025) are discussed, with insights from the perspective of an expert patient and physician experienced in the field of multiple myeloma (MM). This podcast aims to enhance the communication and understanding of complex scientific data on MM among a broad audience, including both specialists and non-specialists, and help guide the partnership between patients and clinicians in making informed treatment decisions.

Three key topics are covered by the podcast: Emerging evidence supporting a shift to earlier use of T-cell directed therapies facilitating an earlier immune response in MM patients; evidence for proactive strategies to optimize the patient outcomes and experience with T-cell-redirecting therapies; and an overview of novel T-cell-directed regimens entering the field for typically difficult-to-treat relapsed/refractory multiple myeloma (RRMM).

Journal- Therapeutic Advances in Hematology

Article title: Shifting Treatment Paradigm in Multiple Myeloma: A Podcast Integrating ASH 2025 Data with Patient and Physician Perspectives

Corresponding author: Rahul Banerjee

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