『Sage Journals Podcast』のカバーアート

Sage Journals Podcast

Sage Journals Podcast

著者： SAGE Publishers
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Podcast Articles

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  • ATTR-CM: What do we know about blood levels of the TTR protein? A discussion with experts

    ATTR-CM: What do we know about blood levels of the TTR protein? A discussion with experts
    2026/02/27
    Proteins are biological machines in living things. A protein called transthyretin, abbreviated as “TTR”’, normally flows in blood to move certain chemicals from one place to another. For normal function, 4 copies of TTR need to be folded together in a specific way. If TTR becomes unfolded or folds the wrong way, it will clump with other TTR proteins. These clumps stick to organ tissues and build up over time. As the sticky clumps grow, they prevent the organs from working properly. When this happens in the heart, it can lead to a weakened heart muscle and eventually death. Acoramidis is a drug that keeps the 4 copies of TTR together and folded correctly. In this medical study, doctors looked at the amount of TTR in the blood of 557 people with misfolded TTR. They found treatment with acoramidis quickly increased the amount of TTR in blood, which lowered the risk of death by more than one-fourth.

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    8 分
  • Shifting Treatment Paradigm in Multiple Myeloma: A Podcast Integrating ASH 2025 Data with Patient and Physician Perspectives

    Shifting Treatment Paradigm in Multiple Myeloma: A Podcast Integrating ASH 2025 Data with Patient and Physician Perspectives
    2026/03/26
    In this plain language podcast, highlights from the 67th American Society of Hematology Annual Meeting and Exposition (ASH 2025) are discussed, with insights from an expert patient and physician experienced in the field of multiple myeloma (MM). This podcast aims to enhance the communication and understanding of complex MM data for both specialists and non-specialists, and support shared patient and physician treatment decision-making. Three key topics are covered by the podcast: Emerging evidence supporting a shift to earlier use of T-cell directed therapies; proactive strategies to optimize patient experience with T-cell-redirecting therapies; and an overview of novel investigational T-cell-directed regimens for relapsed/refractory multiple myeloma (RRMM).

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    43 分
  • Patient Voices and Clinical Advances: Elinzanetant for Menopause Symptom Management Associated With Breast Cancer Treatment in the OASIS-4 Trial

    Patient Voices and Clinical Advances: Elinzanetant for Menopause Symptom Management Associated With Breast Cancer Treatment in the OASIS-4 Trial
    2026/06/22

    In this podcast, a moderator interviews an oncologist and a patient with lived experience of breast cancer on the topic of hot flashes and sleep disturbances in women receiving endocrine therapy for breast cancer treatment. The podcast focuses on key results from the OASIS-4 clinical study of elinzanetant, a dual neurokinin(NK)-1 and NK-3 targeted treatment that blocks the source of hot flashes. Participants reflect on the broader relevance of the results in symptom management, endocrine therapy treatment compliance, and treatment outcomes for patients with breast cancer without compromising their quality of life.


    The medicines and indications discussed in this journal are not licensed in all countries, including the United Kingdom. This content is not intended for healthcare professionals in countries where these medicines or indications are not licensed.


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    32 分
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