Non-communicable diseases (NCDs) increasingly represent a leading cause of morbidity and mortality among people with HIV. People with HIV are at high risk of developing NCDs, often at younger ages and more severely than people without HIV.

Esteban Martinez from the Hospital Clinic and University of Barcelona, and Steven Grinspoon from the Massachusetts General Hospital and Harvard Medical School, join us to explore the importance of NCDs and how data from the REPRIEVE trial can help us understand and prevent the underlying causes increasing the risk of NCDs in people with HIV.

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https://www.thelancet.com/journals/lanhiv/article/PIIS2352-3018(26)00031-7/fulltext https://www.thelancet.com/journals/lanhiv/article/PIIS2352-3018(25)00354-6/fulltext https://www.thelancet.com/journals/lanhiv/article/PIIS2352-3018(26)00036-6/fulltext

People living with HIV often have many health needs beyond their antiretroviral medication. Editor in Chief Peter Hayward talks to Colette Smith of the Institute for Global Health at University College London about results of the Positive Voices survey identifying unmet health needs for people with HIV in the UK.

Click here to read the full article: https://www.thelancet.com/journals/lanhiv/article/PIIS2352-3018(25)00332-7/fulltext

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Ageing with HIV brings new challenges. Even with effective ART, people ageing with HIV face increased risk of parkinsonism. Eran F Shorer from the Icahn School of Medicine at Mount Sinai joins us to explore the latest research on brain changes, motor slowing, and the need for better diagnosis and treatment.

https://www.thelancet.com/journals/lanhiv/article/PIIS2352-3018(25)00262-0/fulltext

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Controlling the HIV epidemic depends on shifting from fragmented, donor-led programmes to nationally led, integrated health systems. To accompany a new joint Series of six papers, Peter Hayward, Editor-in-chief of The Lancet HIV, and Gavin Cleaver, Senior Editor at The Lancet Global Health, are joined in conversation by Solange Baptiste, Kenneth Ngure, and Charles Holmes, who worked extensively on the Series. Together they discuss withstanding external funding shocks, meaningful community involvement, and focusing on health equity, as part of a sustainable approach to HIV prevention in Africa.

Click here to read the full series: https://www.thelancet.com/series-do/sustainable-hiv-prevention-africa

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Why do some people living with HIV struggle with sleep? Luxena Sukuraman and Alan Winston help us understand the challenges of disordered sleep in HIV, what clinicians can do to help, and practical sleep hygiene tips for people living with HIV experiencing sleep disturbances.

Click here to read the full article: https://www.thelancet.com/journals/lanhiv/article/PIIS2352-3018(25)00221-8/fulltext

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In the ongoing search for an HIV cure, promising evidence suggests that early treatment of infants might help achieve lasting HIV remission: the IMPAACT P1115 study is designed to investigate that potential. We talk to a lead investigator about what we know so far.

Read the full article: www.thelancet.com/journals/lanhiv/article/PIIS2352-3018(25)00189-4/fulltext

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Despite advances in treatment, HIV-associated cryptococcal meningitis continues to carry a high risk of death in Africa. In this episode, Jayne Ellis from the London School of Hygiene and Tropical Medicine discusses new research showing why targeting cytomegalovirus could be key to improving outcomes for people living with advanced HIV.

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https://www.thelancet.com/journals/lanhiv/article/PIIS2352-3018(25)00163-8/fulltext?dgcid=buzzsprout_icw_podcast_October_25_lanhiv

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Although some countries are making great headway in eliminating vertical transmission of HIV, more than 100 000 infants acquire HIV each year. Maggie Walters and Michelle Bulterys talk us through their research into factors that affect the probability of vertical transmission and what it says about efforts to end new infant acquisitions.

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https://www.thelancet.com/journals/lanhiv/article/PIIS2352-3018(25)00132-8/fulltext?dgcid=buzzsprout_icw_podcast_August_25_lanhiv

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